Survey of Ophthalmology
Volume 45, Supplement 2 , Pages S221-S226, March 2001

Diagnosis of Dry Eye

  • Anthony J Bron, BSc, FRCOphth

      Affiliations

    • Corresponding Author InformationReprint address: Professor Anthony J Bron, Nuffield Laboratory of Ophthalmology, Walton Street, Oxford, OX2 6AW, UK

Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, United Kingdom

Abstract 

Dry eye disease is characterized by symptoms, ocular surface damage, reduced tear film stability, and tear hyperosmolarity. There are also inflammatory components. These features can be identified by various kinds of diagnostic tests (symptom questionnaires, ocular surface staining, tear break-up time, and osmometry), although there may not be a direct correlation between the number or severity of symptoms and the degree of ocular surface damage or tear deficiency. Once the diagnosis of dry eye disease has been established, further tests can be used to classify the condition into tear-deficient or evaporative dry eye. The two forms of dry eye are not mutually exclusive and often co-exist. The optimal diagnosis of dry eye disease, therefore, depends on the results of several tests, and this article suggests an appropriate order for performing these tests at a single clinic visit.

Keywords:  rose bengal, diagnosis, dry eye disease, fluorescein, meniscometry, osmolarity, phenol red, tear break-up time

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PII: S0039-6257(00)00201-0

Survey of Ophthalmology
Volume 45, Supplement 2 , Pages S221-S226, March 2001