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Survey of Ophthalmology
Volume 45
, Pages S284-S289
, May 2001
Efficacy and Safety of Memantine, an NMDA-Type Open-Channel Blocker, for Reduction of Retinal Injury Associated with Experimental Glaucoma in Rat and Monkey
References
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- . Memantine in the treatment of mild to moderate dementia syndrome. A double-blind placebo-controlled study. Arzneimittelforschung. 1992;42:904–913
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Gu Z, Yamamoto T, Kawase C, et al: [Neuroprotective effect of N-methyl-D-aspartate receptor antagonists in an experimental glaucoma model in the rat]. Nippon Ganka Gakkai Zasshi 104:11–6, 2000
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Electrophysiological and histological measures of retinal injury in chronic ocular hypertensive monkeys.
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Functional measures of inner retinal damage following acute retinal ischemia with and without pretreatment with NMDA antagonists.
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- Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5- dimethyladamantan). Neuropharmacology. 1993;32:1337–1350
- Chronic low-dose glutamate is toxic to retinal ganglion cells. Toxicity blocked by memantine. Invest Ophthalmol Vis Sci. 1996;37:1618–1624
- . Memantine in severe dementia (results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine)). Int J Geriatr Psychiatry. 1999;14:135–146
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☆ The authors are employed by Allergan, Inc., Irvine, CA, USA.
PII: S0039-6257(01)00200-4
© 2001 Elsevier Science Inc. All rights reserved.
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Survey of Ophthalmology
Volume 45
, Pages S284-S289
, May 2001
