Survey of Ophthalmology
Volume 47, Issue 1 , Pages 36-41 , January 2002

Two Discrete Choroidal Melanomas in an Eye with Ocular Melanocytosis

  • Santosh G Honavar, MD

      Affiliations

    • Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA USA
    • Ocular Oncology Service, LV Prasad Eye Institute, Hyderabad, India
    • ,
  • Carol L Shields, MD

      Affiliations

    • Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA USA
    • Corresponding Author InformationReprint address: Carol L. Shields, MD, Oncology Service, Wills Eye Hospital, 900 Walnut Street, Philadelphia, PA, 19107
    • ,
  • Arun D Singh, MD

      Affiliations

    • Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA USA
    • ,
  • Hakan Demirci, MD

      Affiliations

    • Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA USA
    • ,
  • Bryan K Rutledge, MD

      Affiliations

    • Retina Vitreous Surgeons, Syracuse, NY, USA
    • ,
  • Jerry A Shields, MD

      Affiliations

    • Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA USA
    • ,
  • Ralph C Eagle Jr, MD

      Affiliations

    • Pathology Department, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA USA

References 

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  2. Condon RA, Mullaney J. Multiple malignant melanomata of the uveal tract in one eye. Br J Ophthalmol. 1967;51:707–711
  3. Dithmar S, Volcker HE, Grossniklaus HE. Multifocal intraocular malignant melanoma (report of two cases and review of the literature). Ophthalmology. 1999;106:1345–1348
  4. Frayer WC. An eye with endothelial dystrophy and multiple malignant melanomata (a histopathologic case report). Arch Ophthalmol. 1956;56:160
  5. Fuchs E. In: Das Sarcom Des Uveal-Tractus. Vienna: W. Braumuller; 1882;p. 10–57
  6. Gonder JR, Ezell PC, Shields JA, Augsburger JJ. Ocular melanocytosis. A study to determine the prevalence rate of ocular melanocytosis. Ophthalmology. 1982;89:950–952
  7. Gonder JR, Shields JA, Albert DM, et al.  Uveal malignant melanoma associated with ocular and oculodermal melanocytosis. Ophthalmology. 1982;89:953–960
  8. Holck DE, Dutton JJ, Pendergast SD, Klintworth GK. Double choroidal malignant melanoma in an eye with apparent clinical regression. Surv Ophthalmol. 1998;42:441–448
  9. Ley AP, Wahl JW. Multiple malignant melanoma of the choroid. Arch Ophthalmol. 1963;70:385–386
  10. Lois N, Shields CL, Shields JA, et al.  Trifocal uveal melanoma. Am J Ophthalmol. 1997;124:848–850
  11. Peer J, Bernstein-Lifshitz L. Case report. Anterior and posterior uveal melanomas in one eye. Arch Ophthalmol. 1988;106:22–23
  12. Pomeranz GA, Bunt AH, Kalina RE. Multifocal choroidal melanoma in ocular melanocytosis. Arch Ophthalmol. 1981;99:857–863
  13. Pressburger E. Uber den befund von zwei sarkomen der aderhaut in einem augapfel. Bericht der Deutschen. Ophthalmologischen Gesellschaft. 1927;46:451–455
  14. Rochat GF. Zwei gleichgrosse sarkome in einem auge. Klin Monatsbl Augenheilkd. 1926;76:651–655
  15. Rosen DA, Moulton GN. Multiple malignant melanomas in one eye. Am J Ophthalmol. 1953;36:73–75
  16. Sabates FN, Yamashita T. Congenital melanosis oculi complicated by two independent malignant melanomas of the choroid. Arch Ophthalmol. 1967;77:801–803
  17. Shields CL, Shields JA, De Potter P, et al.  Diffuse choroidal melanoma. Clinical features predictive of metastasis. Arch Ophthalmol. 1996;114:956–963
  18. Shields JA, Shields CL. In: Intraocular Tumors (A Text and Atlas). Philadelphia: WB Saunders; 1992;p. 45–59
  19. Singh AD, De Potter P, Fijal BA, et al.  Lifetime prevalence of uveal melanoma in white patients with oculo(dermal) melanocytosis. Ophthalmology. 1998;105:195–198
  20. Singh AD, Shields CL, Shields JA, De Potter P. Bilateral primary uveal melanoma. Bad luck or bad genes?. Ophthalmology. 1996;103:256–262
  21. Tappin MJ, Parsons MA, Sisley K, et al.  Two cases of double melanoma of the uvea. Eye. 1996;10:600–602
  22. Velazquez N, Jones IS. Ocular and oculodermal melanocytosis associated with uveal melanoma. Ophthalmology. 1983;90:1472–1476
  23. Velhagen C. Ueber den befund von zwei choroidealsarkomen in einem augapfel. Klin Monatsbl Augenheilkd. 1920;64:252–255
  24. Volcker HE, Naumann GO. Multicentric primary malignant melanomas of the choroid (two separate malignant melanomas of the choroid and two uveal naevi in one eye). Br J Ophthalmol. 1978;62:408–413

PII: S0039-6257(01)00281-8

Survey of Ophthalmology
Volume 47, Issue 1 , Pages 36-41 , January 2002

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