Survey of Ophthalmology
Volume 48, Issue 1 , Pages 1-11, January 2003

Acute Macular Neuroretinopathy:

A Review of the Literature

  • Sean D Turbeville, PhD

      Affiliations

    • Corresponding Author InformationReprint address: Sean D. Turbeville, PhD, 413 NW 46th Street, Oklahoma City, OK 73118, USA
    • Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK USA
    • ,
  • Linda D Cowan, PhD

      Affiliations

    • Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK USA
    • ,
  • J.Donald M Gass, MD

      Affiliations

    • Vanderbilt Eye Clinic, Nashville, TN, USA

Abstract 

Acute macular neuroretinopathy (AMNR) is a rare condition that produces transient or permanent visual impairment. Typical cases have acute onset multifocal scotomas that correspond rather precisely with reddish, flat, or depressed circumscribed lesions in the macula. These lesions are wedge-shaped and generally point toward the fovea. The pathophysiology of AMNR is unclear, the causes are uncertain, and there is no specific treatment for this condition. This review summarizes the presentation, possible risk factors, and prognosis of the 41 cases of AMNR reported in the published, English-language literature from 1975 through April 2002. Possible areas for future research into the etiology of this rare condition are discussed.

Keywords:  case reports, etiology, maculopathy, pathophysiology, retinopathy, review

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PII: S0039-6257(02)00398-3

Survey of Ophthalmology
Volume 48, Issue 1 , Pages 1-11, January 2003

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