Survey of Ophthalmology
Volume 49, Issue 2 , Pages 231-236, March 2004

A Childhood cavernous conundrum

  • Andrew G. Lee, MD

      Affiliations

    • Corresponding Author InformationReprint address: Andrew G. Lee, M.D. 200 Hawkins Drive, PFP, The University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242.
  • ,
  • Susan J. Quick, MD

      Affiliations

Departments of 1Ophthalmology, 2Neurology, and 3Neurosurgery, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA

PETER J. SAVINO AND HELEN DANESH-MEYER, EDITORS

Abstract 

A 9-year-old boy presented with a left-sided “tooth ache.” Subsequently, he developed new onset vertical diplopia. He was found to have a left cranial nerve three palsy. Cranial magnetic resonance imaging showed bilateral cavernous sinus lesions that were initially interpreted as possible “cavernous sinus thrombosis.” Subsequent blood smear and bone marrow biopsy disclosed Burkitt lymphoma. He was treated with chemotherapy and made a dramatic recovery. Burkitt lymphoma rarely presents with a third nerve palsy but should be considered in the differential diagnosis of childhood cavernous sinus syndrome.

Keywords: Burkitt lymphoma, cavernous sinus, cranial nerve III palsy

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 This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York, NY. The authors reported no proprietary or commercial interest in any product mentioned or concept discussed in this review.

PII: S0039-6257(03)00185-1

doi:10.1016/j.survophthal.2003.12.011

Survey of Ophthalmology
Volume 49, Issue 2 , Pages 231-236, March 2004