Survey of Ophthalmology
Volume 50, Issue 1 , Pages 3-13, January 2005

Systemic and intraocular manifestations of West Nile virus infection

  • Seema Garg, MD, PhD
    • ,
  • Lee M. Jampol, MD

      Affiliations

    • Corresponding Author InformationReprint address: Lee M. Jampol, MD, 645 N. Michigan Ave., Suite 440, Chicago, IL 60611.

Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois

Abstract 

Since the introduction of West Nile virus in the Western Hemisphere in 1999, the incidence of human infection has increased dramatically. As this virus spreads westward across the United States, ophthalmologists should be aware of this presently uncommon but important condition. Systemic features of West Nile virus infection are well characterized; however, the ophthalmic presentations are not widely known. Intraocular involvement with West Nile virus infection was first described in February 2003, and a variety of ophthalmic manifestations have since been recognized. A complete survey of the systemic and intraocular manifestations of West Nile virus infection relevant to the ophthalmologist is presented.

Key words: chorioretinitis, eye, ischemia, neovascularization, optic neuritis, uveitis, vasculitis, West Nile virus

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 Supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York City. The authors reported no proprietary or commercial interest in any product mentioned or concept discussed in this article. Dr Jampol is a member of Survey of Ophthalmology's Editorial Board. The authors would like to thank Samuel Alpert as well as the American Journal of Ophthalmology for the use of their photograph. We thank Jonathan Shankle, CRA, and John Gerty, CRA, our ophthalmic photographers.

PII: S0039-6257(04)00156-0

doi:10.1016/j.survophthal.2004.10.001

Survey of Ophthalmology
Volume 50, Issue 1 , Pages 3-13, January 2005

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