Survey of Ophthalmology
Volume 50, Issue 1 , Pages 27-47 , January 2005

Laser flare-cell photometry: methodology and clinical applications

  • John G. Ladas, MD, PhD

      Affiliations

    • Ocular Inflammatory Disease Center, Jules Stein Eye Institute
    • Departments of Ophthalmology
  • ,
  • Noel C. Wheeler, PhD

      Affiliations

    • Biomathematics, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
  • ,
  • Patrick J. Morhun, MD

      Affiliations

    • Ocular Inflammatory Disease Center, Jules Stein Eye Institute
    • Departments of Ophthalmology
  • ,
  • Steven O. Rimmer, MD

      Affiliations

    • Ocular Inflammatory Disease Center, Jules Stein Eye Institute
    • Departments of Ophthalmology
  • ,
  • Gary N. Holland, MD

      Affiliations

    • Ocular Inflammatory Disease Center, Jules Stein Eye Institute
    • Departments of Ophthalmology
    • Corresponding Author InformationReprint address: Gary N. Holland, MD, Jules Stein Eye Institute, 100 Stein Plaza, UCLA, Los Angeles, CA 90095-7003.

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 Dr. Ladas is now affiliated with the Wilmer Ophthalmological Institute, Johns Hopkins School of Medicine, Baltimore, MD. Dr. Wheeler has recently been affiliated with, and is now retired from, the Department of Statistics, California Polytechnic State University, San Luis Obispo, CA. Supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York, NY, (Dr. Holland), the Skirball Foundation, Los Angeles, CA (Dr. Holland), and the David May II Endowed Professorship (Dr. Holland). Dr. Holland is a recipient of a Research to Prevent Blindness Physician-Scientist Award. Fei Yu, PhD, of the Jules Stein Eye Institute Clinical Research Center provided assistance with the critical review of statistical methods described in selected publications cited in this article. The FC-1000 was provided by Kowa Company, Ltd., Electronics and Optics Division, Tokyo, Japan, for generation of the original research data presented herein. Dr. Holland was an unpaid member of the Kowa Laser Flare-Cell Photometry Medical Advisory Board from 1991 to 1995. The authors have no other interest in the products or techniques described in this report or in competing techniques.Members of the Kowa Laser Flare-Cell Photometry Medical Advisory Board were: Rubens Belfort, Jr., MD, PhD (Sao Paulo, Brazil), Robert C. Drews, MD (Clayton, MO), Gary N. Holland, MD (Los Angeles, CA), Carl Herbort, MD, PhD (Lausanne, Switzerland), Robert B. Nussenblatt, MD (Chairman; Bethesda, MD), David J. Spalton, MD (London, UK), and Scott M. Whitcup, MD (Bethesda, MD). Dr. Whitcup is currently located in Irvine, CA. The opinions expressed herein are those of the authors, and may or may not be shared by other members of the Kowa Laser Flare-Cell Photometry Medical Advisory Board.

PII: S0039-6257(04)00159-6

doi: 10.1016/j.survophthal.2004.10.004

Survey of Ophthalmology
Volume 50, Issue 1 , Pages 27-47 , January 2005