Survey of Ophthalmology
Volume 51, Issue 1 , Pages 75-85 , January 2006

Depth-of-Focus of the Human Eye: Theory and Clinical Implications

  • Bin Wang, MS, MD

      Affiliations

    • Corresponding Author InformationReprint address: Bin Wang, MS, MD, Department of Vision Sciences, SUNY/State College of Optometry, 33 West 42nd Street, New York, NY 10036.
    • ,
  • Kenneth J. Ciuffreda, OD, PhD

References 

  1. Akutsu H, Legge GE, Showalter M, et al. Contrast sensitivity and reading through multifocal intraocular lenses. Arch Ophthalmol. 1992;110:1076–1080
  2. Alpern M. Variability of accommodation during steady fixation at various levels of illumination. J Opt Soc Am. 1958;48:193–197
  3. Artal P, Chen L, Fernández EJ, et al. Neural compensation for the eye's optical aberrations. J Vis. 2004;4:281–287
  4. Artal P, Chen L, Fernández EJ, et al. Adaptive optics for vision: the eye's adaptation to point spread function. J Refract Surg. 2003;19:S585–S587
  5. Atchison DA, Charman WN, Woods RL. Subjective depth-of-focus of the eye. Opt Vis Sci. 1997;74:511–520
  6. Auffarth GU, Hunold W, Wesendahl TA, et al. Depth of focus and functional results in patients with multifocal intraocular lenses: a long-term follow-up. J Cataract Refract Surg. 1993;19:685–689
  7. Banks MS. The development of visual accommodation during early infancy. Child Dev. 1980;51:646–666
  8. Borish IM, Benjamin WJ. Monocular and binocular subjective refraction. In:  Benjamin WJ editors. Borish's Clinical Refraction: Principles and Practice. Philadelphia: Saunders; 1998;p. 629–723
  9. Campbell FW. The depth of field of the human eye. Opt Acta. 1957;4:157–164
  10. Campbell FW. The minimum quantity of light required to elicit the accommodation reflex in man. J Physiol. 1954;123:357–366
  11. Campbell FW, Westheimer G. Sensitivity of the eye to differences in focus. J Physiol. 1958;143:18
  12. Charman WN, Jennings JA. The optical quality of the monochromatic retinal image as a function of focus. Br J Physiol Opt. 1976;31:119–134
  13. Charman WN, Whitefoot H. Pupil diameter and the depth-of-field of the human eye as measured by laser speckle. Opt Acta. 1977;24:1211–1216
  14. Cheng X, Bradley A, Hong X, et al. Relationship between refractive error and monochromatic aberrations of the eye. Opt Vis Sci. 2003;80:43–49
  15. Cho MH, Benjamin WJ. Correction with multifocal spectacle lenses. In:  Benjamin WJ editors. Borish's Clinical Refraction: Principles and Practice. Philadelphia: Saunders; 1998;p. 888–927
  16. Ciuffreda KJ. The scientific basis for and efficacy of optometric vision therapy in nonstrabismic accommodative and vergence disorders. Optometry. 2002;73:735–762
  17. Ciuffreda KJ. Accommodation and its anomalies. In:  Charman WN editors. Vision and Visual Dysfunction. Vol. 1:London: MacMillan; 1991;p. 231–279
  18. Ciuffreda KJ. Accommodation, pupil, and presbyopia. In:  Benjamin WJ editors. Borish's Clinical Refraction: Principles and Practice. Philadelphia: Saunders; 1998;p. 77–120
  19. Ciuffreda KJ, Hokoda SC, Hung GK, et al. Static aspects of accommodation in human amblyopia. Am J Opt Physiol Opt. 1983;60:436–449
  20. Ciuffreda KJ, Hokoda SC, Hung GK, et al. Accommodative stimulus/response function in human amblyopia. Doc Ophthalmol. 1984;56:303–326
  21. Ciuffreda KJ, Levi DM, Selenow A: Amblyopia: Basic and Clinical Aspects. Boston, Butterworth, l991
  22. Ciuffreda KJ, Tannen B. Training of nystagmus: a multi-sensory approach. J Behav Optom. 1999;10:63–66
  23. Ciuffreda KJ, Tannen B, Rutner D. Multi-sensory feedback therapy for oculomotor dysfunction. In:  Hung GK,  Ciuffreda KJ editor. Models of the Visual System. New York: Kluwer/Plenum; 2002;p. 741–769
  24. Ciuffreda KJ, Wang B, Wong D. Central and near peripheral retinal contributions to the depth-of-focus using natural stimulation. Vision Res. 2005;45:2650–2658
  25. Doane JF. Accommodating intraocular lenses. Curr Opin Ophthalmol. 2004;15:16–21
  26. Duke-Elder W, Abrams D: System of Ophthalmology (Vol. V): Ophthalmic Optics and Refraction. St. Louis, MO, Mosby, 1970, pp 383–5
  27. Efron N. Contact Lenses A–Z. Boston: Butterworth-Heinemann; 2002;
  28. George S, Rosenfield M. Blur adaptation and myopia. Opt Vis Sci. 2004;81:543–547
  29. Green DG, Powers MK, Banks MS. Depth of focus, eye size and visual acuity. Vision Res. 1980;20:827–835
  30. Gwiazda J, Thorn F, Bauer J, et al. Myopic children show insufficient accommodative response to blur. Invest Ophthalmol Vis Sci. 1993;34:690–694
  31. Hall EC, Ciuffreda KJ. Eccentric viewing training in macular degeneration using auditory ocular motor biofeedback. J Behav Optom. 2001;12:87–93
  32. He JC, Sun P, Held R, et al. Wavefront aberrations in eyes of emmetropic and moderately myopic school children and young adults. Vision Res. 2002;42:1063–1070
  33. Heath GG. Accommodative responses of totally color blind observers. Am J Opt Arch Am Acad Opt. 1956;33:457–465
  34. Heath GG. The influence of visual acuity on accommodative response of the human eye. Am J Opt Arch Am Acad Opt. 1956;33:513–524
  35. Hung GK. Models of Oculomotor Control. River Edge, NJ: World Scientific Publishing; 2001;
  36. Hung GK, Ciuffreda KJ. Models of refractive error development. In:  Hung GK,  Ciuffreda KJ editor. Models of the Visual System. New York: Kluwer/Plenum; 2002;p. 643–677
  37. Jacobs RJ, Smith G, Chan CD. Effect of defocus on blur thresholds and on thresholds of perceived change in blur: comparison of source and observer methods. Opt Vis Sci. 1989;66:545–553
  38. Jiang BC, Morse SE. Oculomotor functions and late-onset myopia. Ophthalmic Physiol Opt. 1999;19:165–172
  39. Kamlesh MS, Dadeya S, Kaushik S. Contrast sensitivity and depth of focus with aspheric multifocal versus conventional monofocal intraocular lens. Can J Ophthalmol. 2001;36:197–201
  40. Kingslake R. Depth of field. In:  Kingslake R editors. Lenses in Photography. New York: Garden City Books; 1951;p. 74–93
  41. Kotulak JC, Schor CM. The accommodative response to subthreshold blur and to perceptual fading during the Troxler phenomenon. Perception. 1986;15:7–15
  42. Legge GE, Mullen KT, Woo GC, et al. Tolerance to visual defocus. J Opt Soc Am A. 1987;4:851–863
  43. Ludlam WM, Wittenberg S, Giglio EJ, et al. Accommodative responses to small changes in dioptric stimulus. Am J Opt Arch Am Acad Opt. 1968;45:483–506
  44. Marcos S. Aberrations and visual performance following standard laser vision correction. J Refract Surg. 2001;17:S596–S601
  45. Marcos S, Moreno E, Navarro R. The depth-of-field of the human eye from objective and subjective measurements. Vision Res. 1999;39:2039–2049
  46. McGill E, Arnes K, Erickson P, et al. Quality of vision with hydrogel simultaneous vision bifocal contact lenses. Int Cont Lens Clinic. 1987;14:476–481
  47. Miege C, Denieul P. Mean response and oscillations of accommodation for various stimulus vergences in relation to accommodation feedback control. Ophthalmic Physiol Opt. 1988;8:165–171
  48. Miles PW. Depth of focus and amplitude of accommodation through trifocal glasses. Arch Ophthalmol. 1953;49:271–279
  49. Montés-Micó R, España E, Bueno I, et al. Visual performance with multifocal intraocular lenses: mesopic contrast sensitivity under distance and near conditions. Ophthalmology. 2004;111:85–96
  50. Mordi JA, Ciuffreda KJ. Static aspects of accommodation: age and presbyopia. Vision Res. 1998;38:1643–1653
  51. Morgan MW. Accommodation and vergence. Am J Opt Arch Am Acad Opt. 1968;45:417–454
  52. Ninomiya S, Maeda N, Kuroda T, et al. Comparison of ocular higher-order aberrations and visual performance between photorefractive keratectomy and laser in situ keratomileusis for myopia. Semin Ophthalmol. 2003;18:29–34
  53. Ogle KN: Optics: An Introduction for Ophthalmologists. Springfield, Illinois, Charles C Thomas, ed 2, 1968
  54. Ogle KN, Schwartz JT. Depth of focus of the human eye. J Opt Soc Am. 1959;49:273–280
  55. Ong E, Ciuffreda KJ. Accommodation, nearwork and myopia. Santa Ana, CA: OEP Foundation Press; 1997;
  56. Ong E, Ciuffreda KJ, Tannen B. Static accommodation in congenital nystagmus. Invest Ophthalmol Vis Sci. 1993;34:194–204
  57. Oshima S. Studies on the depth-of-focus of the eye. Jap J Ophthalmol. 1958;2:63–72
  58. Pearce JL. Multifocal intraocular lenses. Curr Opin Ophthalmol. 1996;7:2–10
  59. Plakitsi A, Charman WN, et al. Comparison of the depth of focus with the naked eye and with three types of presbyopic contact lens correction. J Br Contact Lens Assoc. 1995;18:119–125
  60. Post CT. Comparison of depth of focus and low-contrast acuities for monofocal versus multifocal intraocular lens patients at 1 year. Ophthalmology. 1992;99:1658–1663discussion 1663–4
  61. Pujol J, Gispets J, Arjona M. Optical performance in eyes wearing two multifocal contact lens designs. Ophthalmic Physiol Opt. 2003;23:347–360
  62. Ronchi L, Fontana A. Laser speckles and the depth-of-field of the human eye. Opt Acta. 1975;22:243–246
  63. Ronchi L, Molesini G, et al. Depth of focus in peripheral vision. Ophthalmic Res. 1975;7:152–157
  64. Rosenfield M, Abraham-Cohen JA. Blur sensitivity in myopes. Opt Vis Sci. 1999;76:303–307
  65. Rosenfield M, Ciuffreda KJ. Accommodative responses to conflicting stimuli. J Opt Soc Am A. 1991;8:422–427
  66. Rosenfield M, Ciuffreda KJ, Rosen J. Accommodative response during distance optometric test procedures. J Am Opt Assoc. 1992;63:614–618
  67. Sawusch MR, Guyton DL. Optimal astigmatism to enhance depth of focus after cataract surgery. Ophthalmology. 1991;98:1025–1029
  68. In:  Schapero M,  Cline D,  Hofstetter HW editor. Dictionary of Visual Science. Radnor, PA: Chilton Book Company; 1968;p. 192
  69. Schwartz SH. Geometrical and Visual Optics: A Clinical Introduction. New York: McGraw-Hill; 2002;
  70. Seiler T, Dastjerdi MH. Customized corneal ablation. Curr Opin Ophthalmol. 2002;13:256–260
  71. Shapiro MB, Bredeson DC. A prospective evaluation of Unilens soft multifocal contact lenses in 100 patients. CLAO J. 1994;20:189–191
  72. Sheedy JE, Harris MG, Bronge MR, et al. Task and visual performance with concentric bifocal contact lenses. Opt Vis Sci. 1991;68:537–541
  73. Stark L. Neurological Control Systems: Studies in Bioengineering. New York: Plenum Press; 1968;
  74. Stark LR, Strang NC, Atchison DA. Dynamic accommodation response in the presence of astigmatism. J Opt Soc Am A Opt Image Sci Vis. 2003;20:2228–2236
  75. Stiles WS. The directional sensitivity of the retina and the spectral sensitivities of the rods and cones. Proc R Soc Lond Biol Sci. 1939;127:64–105
  76. Thibos LN, Hong X. Clinical applications of the Shack-Hartmann aberrometer. Opt Vis Sci. 1999;76:817–825
  77. Tucker J, Charman WN. Depth of focus and accommodation for sinusoidal gratings as a function of luminance. Am J Opt Physiol Opt. 1986;63:58–70
  78. Tucker J, Charman WN. The depth-of-focus of the human eye for Snellen letters. Am J Opt Physiol Opt. 1975;52:3–21
  79. Von Bahr G. Studies on the depth of focus of the eye. Acta Ophthalmol. 1952;30:39–44
  80. Waheed S, Krueger RR. Update on customized excimer ablations: recent developments reported in 2002. Curr Opin Ophthalmol. 2003;14:198–202
  81. Walsh G, Charman WN. Visual sensitivity to temporal change in focus and its relevance to the accommodation response. Vision Res. 1988;28:1207–1221
  82. Wang B, Ciuffreda KJ. Depth-of-focus of the human eye in the near retinal periphery. Vision Res. 2004;44:1115–1125
  83. Wang YZ, Thibos LN, Bradley A. Effects of refractive error on detection acuity and resolution acuity in peripheral vision. Invest Ophthalmol Vis Sci. 1997;38:2134–2143
  84. Ward PA, Charman WN. On the use of small artificial pupils to open-loop the accommodation system. Ophthalmic Physiol Opt. 1987;7:191–193
  85. Webster MA, Georgeson MA, Webster SM. Neural adjustments to image blur. Nat Neurosci. 2002;5:839–840
  86. Winn B, Charman WN, Pugh JR, et al. Perceptual detectability of ocular accommodation microfluctuations. J Opt Soc Am A. 1989;6:459–462
  87. Winn B, Gilmartin B. Current perspective on microfluctuations of accommodation. Ophthalmic Physiol Opt. 1992;12:252–256
  88. Winn B, Pugh JR, Gilmartin B, et al. Arterial pulse modulates steady-state ocular accommodation. Curr Eye Res. 1990;9:971–975
  89. Woods C, Ruston D, Hough T, et al. Clinical performance of an innovative back surface multifocal contact lens in correcting presbyopia. CLAO J. 1999;25:176–181

 The authors reported no proprietary or commercial interest in any product mentioned or concept discussed in this article. The authors would like to thank Dr. Mark Rosenfield for his suggestions and review of an early version of portions of the manuscript.

PII: S0039-6257(05)00194-3

doi: 10.1016/j.survophthal.2005.11.003

Survey of Ophthalmology
Volume 51, Issue 1 , Pages 75-85 , January 2006

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