Survey of Ophthalmology
Volume 51, Issue 2 , Pages 169-173 , March 2006

New Ways To Look at an Old Problem

  • G. Rebolleda, MD, PhD

      Affiliations

    • Ophthalmology Department, Ramon y Cajal Hospital, Madrid, Spain
    • ,
  • F.J. Muñoz-Negrete, MD, PhD

      Affiliations

    • Ophthalmology Department, Ramon y Cajal Hospital, Madrid, Spain
    • ,
  • S. Noval, MD

      Affiliations

    • Ophthalmology Department, Ramon y Cajal Hospital, Madrid, Spain
    • ,
  • I. Contreras, MD

      Affiliations

    • Ophthalmology Department, Ramon y Cajal Hospital, Madrid, Spain
    • ,
  • Molly E. Gilbert, MD

      Affiliations

    • Neuro-ophthalmology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    • Corresponding Author InformationReprint address: Molly E. Gilbert, MD, 840 Walnut St., Suite 930, Philadelphia, PA 19107.
    • ,
  • Robert C. Sergott, MD

      Affiliations

    • Neuro-ophthalmology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

References 

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  11. Li DK, Paty DW. Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta1a in relapsing-remitting multiple sclerosis. Prevention of Relapses and Disability by Interferon-beta1a Subcutaneously in Multi. Ann Neurol. 1999;46:197–206
  12. Panitch H, Goodin DS, Francis G, et al. Randomized, comparative study of interferon beta-1a treatment regimens in MS: The EVIDENCE Trial. Neurology. 2002;59:1496–1506
  13. Parisi V, Manni G, Spadaro M, et al. Correlation between morphological and functional retinal impairment in multiple sclerosis patients. Invest Ophthalmol Vis Sci. 1999;40:2520–2527
  14. Trapp BD, Peterson J, Ransohoff RM, et al. Axonal transection in the lesions of multiple sclerosis. N Engl J Med. 1998;338:278–285
  15. Trip SA, Schlottmann PG, Jones SJ, et al. Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis. Ann Neurol. 2005;58:383–391
  16. Truyen L, van Waesberghe JH, van Walderveen MA, et al. Accumulation of hypointense lesions (“black holes”) on T1 spin-echo MRI correlates with disease progression in multiple sclerosis. Neurology. 1996;47:1469–1476
  17. van Walderveen MA, Kamphorst W, Scheltens P, et al. Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis. Neurology. 1998;50:1282–1288

 The authors reported no proprietary or commercial interest in any product mentioned or concept discussed in this article.

PII: S0039-6257(05)00207-9

doi: 10.1016/j.survophthal.2005.12.002

Survey of Ophthalmology
Volume 51, Issue 2 , Pages 169-173 , March 2006

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