Survey of Ophthalmology
Volume 51, Issue 4 , Pages 364-380, July 2006

Ocular Oxygenation and the Treatment of Diabetic Retinopathy

  • Einar Stefánsson, MD, PhD

      Affiliations

    • Corresponding Author InformationReprint address: Einar Stefánsson, Professor of Ophthalmology, University of Iceland, Department of Ophthalmology, Landspitalinn, 101 Reykjavik, Iceland.

University of Iceland, Department of Ophthalmology, Landspitalinn, Reykjavik, Iceland

Abstract 

Retinal photocoagulation and vitrectomy both reduce diabetic macular edema and neovascularization in diabetic retinopathy. We suggest that this clinical effect is based on the effect these treatment modalities have on retinal oxygenation, and we present a theory to explain why retinal photocoagulation and vitrectomy influence edema and neovascularization in diabetic and other ischemic retinopathies.

Key words: diabetic retinopathy, ischemia, macular edema, neovascularization, oxygen, retinal laser treatment, vitreous surgery

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 The author reported no proprietary or commercial interest in any product mentioned or concept discussed in this article.

PII: S0039-6257(06)00078-6

doi:10.1016/j.survophthal.2006.04.005

Survey of Ophthalmology
Volume 51, Issue 4 , Pages 364-380, July 2006

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