Survey of Ophthalmology
Volume 55, Issue 2 , Pages 134-145 , March 2010

Uveal Effusion Syndrome

  • Mohammed Elagouz, MD

      Affiliations

    • Department of Ophthalmology, King's College Hospital, London, United Kingdom
    • Department of Ophthalmology, Sohag University Hospital, Sohag, Egypt
  • ,
  • Dinu Stanescu-Segall, MD

      Affiliations

    • Department of Ophthalmology, King's College Hospital, London, United Kingdom
  • ,
  • Timothy L. Jackson, PhD, FRCOphth

      Affiliations

    • Department of Ophthalmology, King's College Hospital, London, United Kingdom
    • King's College London, London, United Kingdom
    • Corresponding Author InformationReprint address: Tim Jackson, PhD, FRCOphth, Consultant Ophthalmic Surgeon, Honorary Senior Lecturer, Department of Ophthalmology, King's College Hospital, Denmark Hill, London, SE5 9RS United Kingdom.

References 

  1. Akduman L, Adelberg DA, Del Priore LV. Nanophthalmic uveal effusion managed with scleral windows and topical mitomycin-C. Ophthalmic Surg Lasers. 1997;28:325–327
  2. Allen KM, Meyers SM, Zegarra H. Nanophthalmic uveal effusion. Retina. 1988;8:145–147
  3. Alm A. Ocular circulation. In:  Hart WM editors. Adler's Physiology of the Eye. 9th ed.. London: Mosby; 1992;chap. 6
  4. Anderson OA, Jackson TL, Singh JK, et al. Human transscleral albumin permeability and the effect of topographical location and donor age. Invest Ophthalmol Vis Sci. 2008;49(9):4041–4045
  5. Benson WE, Shields JA, Annesley WH, et al. Idiopathic central serous choroidopathy with bullous retinal detachment. Ann Ophthalmol. 1980;12:920
  6. Bill A. Movement of albumin and dextran through the sclera. Arch Ophthalmol. 1965;74:248–252
  7. Bill A, Wahlinder PE. The effects of pilocarpine on the dynamics of aqueous humor in a primate (Macaca irus). Invest Ophthalmol. 1966;5:170–175
  8. Boubriak OA, Urban JP, Bron AJ. Differential effects of aging on transport properties of anterior and posterior human sclera. Exp Eye Res. 2003;76:701–703
  9. Boubriak OA, Urban JP, Akhtar S, et al. The effect of hydration and matrix composition on solute diffusion in rabbit sclera. Exp Eye Res. 2000;71:503–514
  10. Brockhurst RJ. Vortex vein decompression for nanophthalmic uveal effusion. Arch Ophthalmol. 1980;98:1987–1990
  11. Brockhurst RJ. Discussion of Gass JDM. Uveal effusion syndrome. A new hypothesis concerning pathogenesis and technique of surgical treatment. Trans Am Ophthalmol Soc. 1983;81:256
  12. Brockhurst RJ. Nanophthalmos with uveal effusion: a new clinical entity. Arch Ophthalmol. 1975;93:1289–1299
  13. Brockhurst RJ. Uveal effusion. In:  Albert DM,  Jakobiec FA editor. Principles and Practice of Ophthalmology: Clinical Practice. Philadelphia, PA: Saunders; 1994;p. 548–559
  14. Brockhurst RJ, Lam KW. Uveal effusion. II. Report of a case with analysis of subretinal fluid. Arch Ophthalmol. 1973;90:399
  15. Calhoun FP. The management of glaucoma in nanophthalmos. Trans Am Ophthalmol Soc. 1975;73:97–122
  16. Casswell AG, Gregor ZJ, Bird AC. The surgical management of uveal effusion syndrome. Eye. 1987;1:115–119
  17. Cintron C, Fujikawa LS, Covington H, et al. Fibronectin in developing rabbit cornea. Curr Eye Res. 1984;4:489
  18. Daniele S, Schepens CL. Can chronic bulbar hypotony be responsible for uveal effusion? Report of two cases. Ophthalmic Surg. 1989;20:872
  19. Davies EWG, Sanders MD, Harry J. Annular serous detachment of the choroid. Trans Ophthalmol Soc UK. 1973;93:145
  20. Duke-Elder S. Normal and abnormal development. Congenital deformities. In:  Duke-Elder S editors. System of Opthalmology, vol. 3. St Louis, MO: CV Mosby; 1964;p. 488
  21. Emi K, Pederson JE, Toris CB. Hydrostatic pressure of the suprachoroidal space. Invest Ophthalmol Vis Sci. 1989;30:233–238
  22. Forrester JV, Lee WR, Kerr PR, Dua HS. The uveal effusion syndrome and trans-scleral flow. Eye. 1990;4:354–365
  23. Gass JDM. Bullous retinal detachment: an unusual manifestation of idiopathic central serous choroidopathy. Am J Ophthalmol. 1973;75:810
  24. Gass JDM. Uveal effusion syndrome: a new hypothesis concerning pathogenesis and technique of surgical treatment. Retina. 1983;3:159–163
  25. Gass JDM, Jallow S. Idiopathic serous detachment of the choroid, ciliary body, and retina (uveal effusion syndrome). Ophthalmology. 1982;89:1018–1032
  26. Jackson TL, Hussain A, Hodgetts A, et al. Human scleral hydraulic conductivity: age-related changes, topographical variation, and potential scleral outflow facility. Invest Ophthalmol Vis Sci. 2006;47:4942–4946
  27. Jackson TL, Hussain A, Morley AMS, et al. Scleral hydraulic conductivity and macromolecular diffusion in patients with uveal effusion syndrome. Invest Ophthalmol Vis Sci. 2008;49:5033–5040
  28. Johnson MW, Gass JDM. Surgical management of the idiopathic uveal effusion syndrome. Ophthalmology. 1990;97:778–785
  29. Kelly DE, Hageman GS, McGregar JA. Uveal compartmentalization in the hamster eye revealed by fine structural and tracer studies: implications for uveoscleral outflow. Invest Ophthalmol Vis Sci. 1983;24:1288–1304
  30. Kerstetter JR, Brubaker RF, Wilson SE. Prostaglandin F2 alpha 1-isopropylester effects on aqueous humor dynamics in human subjects. Invest Ophthalmol Vis Sci. 1987;28(Suppl):266
  31. Kimbrough RL, Trempe CL, Brockhurst RJ, et al. Angle-closure glaucoma in nanophthalmos. Am J Ophthalmol. 1979;88:572
  32. Kumar A, Kedar S, Singh RP. The indocyanine green findings in idiopathic uveal effusion syndrome. Indian J Ophthalmol. 2002;50:217–219
  33. Kumar RS, Quek D, Lee KY, et al. Confirmation of the presence of uveal effusion in Asian eyes with primary angle closure glaucoma: an ultrasound biomicroscopy study. Arch Ophthalmol. 2008;126(12):1647–1651
  34. Lam A, Sambursky RP, Maguire JI. Measurement of scleral thickness in uveal effusion syndrome. Am J Ophthalmol. 2005;140(2):329–331
  35. Levick JR. Flow through interstitium and other fibrous matrices. Q J Exp Physiol. 1987;72:409–437
  36. Okabe H, Kiyosawa M, Katsuyoshi M, et al. Nuclear magnetic resonance imaging of subretinal fluid. Am J Ophthalmol. 1986;102:640
  37. Olsen TW, Aaberg SY, Geroski DH, Edelhauser HF. Human sclera: thickness and surface area. Am J Ophthalmol. 1998;125:237–241
  38. Pederson JE, Gaasterland DE, MacLellan HM. Uveoscleral aqueous outflow in the rhesus monkey: importance of uveal reabsorption. Invest Ophthalmol Vis Sci. 1977;16:1008
  39. Pederson JE, Gaasterland DE, MacLellan HM. Experimental ciliochoroidal detachment: effect on intraocular pressure and aqueous flow. Arch Ophthalmol. 1979;97:546
  40. Ryan EA, Zwaan J, Chylack LT. Nanophthalmos with uveal effusion. Clinical and embryologic considerations. Ophthalmology. 1982;89:1013–1017
  41. Sakai H, Morine-Shinjyo S, Shinzato M, et al. Uveal effusion in primary angle–closure glaucoma. Ophthalmology. 2005;112(3):413–419
  42. Sakai H, Sakima N, Nakamura Y, et al. Ciliochoroidal effusion induced by topical latanoprost in a patient with Sturge-Weber syndrome. Jpn J Ophthalmol. 2002;46:553–555
  43. Schepens CL, Brockhurst RJ. Uveal effusion. I. Clinical picture. Arch Ophthalmol. 1963;70:189–201
  44. Shaffer RN. Discussion of: Calhoun FP Jr. The management of glaucoma in nanophthalmos. Trans Am Ophthalmol Soc. 1975;73:96–122119–20
  45. Stewart JM, Schultz DS, Lee OT, Trinidad ML. Exogenous collagen cross-linking reduces scleral permeability: modeling the effects of age-related cross-link accumulation. Invest Ophthalmol Vis Sci. 2009;50(1):352–357
  46. Suzuki Y, Nishina S, Azuma N. Scleral window surgery and topical mitomycin C for nanophthalmic uveal effusion complicated by renal failure. Graefe's Arch Clin Exp Ophthalmol. 2007;245:755–757
  47. Toris CB, Pederson JE. Aqueous humor dynamics in experimental iridocyclitis. Invest Ophthalmol Vis Sci. 1987;28:477
  48. Trelstad RL, Silbermann NN, Brockhurst RJ. Nanophthalmic sclera: ultrastructural, histochemical, and biochemical observations. Arch Ophthalmol. 1982;100:1935–1938
  49. Uyama M, Takahashi K, Kozaki J, et al. Uveal effusion syndrome—clinical features, surgical treatment, histologic examination of the sclera, and pathophysiology. Ophthalmology. 2000;107:441–449
  50. Ward RC, Gragoudas ES, Pon DM, Albert DM. Abnormal scleral findings in uveal effusion syndrome. Am J Ophthalmol. 1988;106:139–146
  51. Wilson RS, Hanna C, Morris MD. Idiopathic chorioretinal effusion: an analysis of extracellular fluids. Ann Ophthalmol. 1977;9:647
  52. Yue BYJT, Duvall J, Goldberg MF, et al. Nanophthalmic sclera: morphologic and tissue culture studies. Ophthalmology. 1986;93:534
  53. Yue BYJT, Kurosawa A, Duvall J, et al. Nanophthalmic sclera. Fibronectin studies. Ophthalmology. 1988;95:56–60

 The authors reported no proprietary or commercial interest in any product mentioned or concept discussed in this article.

PII: S0039-6257(09)00159-3

doi: 10.1016/j.survophthal.2009.05.003

Survey of Ophthalmology
Volume 55, Issue 2 , Pages 134-145 , March 2010