Survey of Ophthalmology
Volume 55, Issue 3 , Pages 227-246 , May 2010

The Role of Complement Factor H in Age-related Macular Degeneration: A Review

  • Larry A. Donoso, MD, PhD

      Affiliations

    • The Philadelphia Retina Endowment Fund, The Eye Research Institute, and the Wills Eye Institute, Philadelphia, Pennsylvania, USA
    • Corresponding Author InformationReprint address: Larry A. Donoso, MD, PhD, PO Box 53429, Philadelphia, PA 19105.
    • ,
  • Tamara Vrabec, MD

      Affiliations

    • The Geisinger Medical Center, Danville, Pennsylvania, USA
    • ,
  • Helena Kuivaniemi, MD, PhD

      Affiliations

    • The Geisinger Medical Center, Danville, Pennsylvania, USA

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 Supported in part by the Elizabeth C. King Trust, in collaboration with the Wills Eye Institute, Philadelphia, PA. Gregory Hageman, PhD, Helga Magargal, MD, Larry Magargal, MD, David Pao, MD, and Drs Carol and Jerry Shields provided helpful discussions. Drs Carol and Jerry Shields provided clinical photographs. The Foundation also acknowledges the support of the residents of Pennswood Village and Twining Village who help to support eye research. Christine Skerka and Paul Barlow provided assistance with some aspects of the text and figures related to Factor H. None of the authors have a commercial interest in any of the pharmaceuticals mentioned in the text or figures.

PII: S0039-6257(09)00300-2

doi: 10.1016/j.survophthal.2009.11.001

Survey of Ophthalmology
Volume 55, Issue 3 , Pages 227-246 , May 2010

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