Survey of Ophthalmology
Volume 55, Issue 5 , Pages 403-428 , September 2010

Tilted Optic Disks

  • Matthew T. Witmer, MD

      Affiliations

    • Department of Ophthalmology, University of South Florida, College of Medicine, Tampa, Florida, USA
    • Corresponding Author InformationReprint address: Dr. Matthew T. Witmer, 12901 Bruce B. Downs Blvd., USF Eye Institute, MDC 21,Tampa, FL 33612.
  • ,
  • Curtis E. Margo, MD, MPH

      Affiliations

    • Department of Ophthalmology, University of South Florida, College of Medicine, Tampa, Florida, USA
    • Department of Pathology, University of South Florida, College of Medicine, Tampa, Florida, USA
  • ,
  • Mitchell Drucker, MD

      Affiliations

    • Department of Ophthalmology, University of South Florida, College of Medicine, Tampa, Florida, USA

References 

  1. Agarwal HC, Gulati V, Sihota R. The normal optic nerve head on Heidelberg retina tomograph 2. Indian J Ophthalmol. 2003;51:25–33
  2. Anderson DR. Correlation of the peripapillary anatomy with the disc damage and full abnormalities in glaucoma. Doc Ophthalmol Proc Ser. 1983;35:1–10
  3. Apple DJ, Rabb MF, Walsh PM. Congenital anomalies of the optic disc. Surv Ophthalmol. 1982;27(1):3–41
  4. Arden GB, Barrada A, Kelsey JH. New clinical test of retinal function based upon the standing potential of the eye. Br J Ophthalmol. 1962;46(8):449–467
  5. Aung T, Foster PJ, Seah SK, et al. Automated static perimetry: the influence of myopia and its method of correction. Ophthalmology. 2001;108(2):290–295
  6. Bagga H, Greenfield D, Feuer W, et al. Quantitative assessment of atypical birefringence images using scanning laser polarimetry with variable corneal compensation. Am J Ophthalmol. 2005;139(3):437–4
  7. Becquet F, Ducournau D, Ducournau Y, et al. Juxtapapillary subretinal pigment epithelial polypoid pseudocysts associated with unilateral tilted optic disc: case report with clinicopathologic correlation. Ophthalmology. 2001;108(9):1657–1662
  8. Bozkurt B, Irkec M, Gedik S, et al. Topographical analysis of corneal astigmatism in patients with tilted disc syndrome. Cornea. 2002;21(5):458–462
  9. Bozkurt B, Irkeç M, Tatlipinar S, et al. Retinal nerve fiber layer analysis and interpretation of GDx parameters in patients with tilted disc syndrome. Int Ophthalmol. 2001;24(1):27–31
  10. Brazitikos PD, Safran AB, Simona F, et al. Threshold perimetry in tilted disc syndrome. Arch Ophthalmol. 1990;108(12):1698–1700
  11. Brodsky MC. Congenital optic disk anomalies. Surv Ophthalmol. 1994;39(2):89–112
  12. Burk RO, Rohrschneider K, Noack H, et al. Are large optic nerve heads susceptible to glaucomatous damage at normal intraocular pressure? A three-dimensional study by laser scanning tomography. Graefes Arch Clin Exp Ophthalmol. 1992;230(6):552–560
  13. Chan CK, Cheng AC, Leung CK, et al. Quantitative assessment of optic nerve head morphology and retinal nerve fibre layer in non-arteritic anterior ischaemic optic neuropathy with optical coherence tomography and confocal scanning laser ophthalmoloscopy. Br J Ophthalmol. 2009;93(6):731–735
  14. Chihara E, Chihara K. Covariation of optic disc measurements and ocular parameters in the healthy eye. Graefes Arch Clin Exp Ophthalmol. 1994;232(5):265–271
  15. Cibis G, Beaver H, Johns K, et al. Organogenesis of the eye, in American Academy of Ophthalmology. Basic and Clinical Science Course, Fundamentals and Principles of Ophthalmology, Section 2. San Francisco, AAO, ed 2008–2009, pp 136–43
  16. Cohen SY, Quentel G. Uneven distribution of drusen in tilted disc syndrome. Retina. 2008;28(9):1361–1362
  17. Cohen SY, Quentel G. Chorioretinal folds as a consequence of inferior staphyloma associated with tilted disc syndrome. Graefes Arch Clin Exp Ophthalmol. 2006;244(11):1536–1538
  18. Cohen SY, Quentel G, Guiberteau B, et al. Macular serous retinal detachment caused by subretinal leakage in tilted disc syndrome. Ophthalmology. 1998;105(10):1831–1834
  19. Danesh-Meyer H, Savino PJ, Spaeth GL, et al. Comparison of arteritis and nonarteritic anterior ischemic optic neuropathies with the Heidelberg Retina Tomograph. Ophthalmology. 2005;112(6):1104–1112
  20. Deleón-Ortega J, Carroll KE, Arthur SN, Girkin CA. Correlations between retinal nerve fiber layer and visual field in eyes with nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol. 2007;143(2):288–294
  21. De Rouck A, Kayembe D, De Laey JJ, et al. Clinical and electrophysiological manifestations of the tilted disk syndrome. Bull Soc Belge Ophtalmol. 1981;193:147–159
  22. Dorrell D. The tilted disc. Br J Ophthalmol. 1978;62(1):16–20
  23. Doshi A, Kreidl KO, Lombardi L, et al. Nonprogressive glaucomatous cupping and visual field abnormalities in young Chinese males. Ophthalmology. 2007;114(3):472–479
  24. Duke-Elder S, Abrams D. Section 2: Ophthalmic Optics and Refraction. In: Duke-Elder S (ed). System of Ophthalmology. St Louis, MO: CV Mosby; 1970;p. 367
  25. Ervin JC, Lemij HG, Mills RP, et al. Clinician change detection viewing longitudinal stereophotographs compared to confocal scanning laser tomography in the LSU Experimental Glaucoma (LEG) Study. Ophthalmology. 2002;109(3):467–481
  26. Flüeler UR, Guyton DL. Does a tilted retina cause astigmatism? The ocular imagery and the retinoscopic reflex resulting from a tilted retina. Surv Ophthalmol. 1995;40(1):45–50
  27. Fuchs E. Beitrage zu den angeboren Anomalien des Sehnerven. Arch Ophthalmol. 1882;28:139–169
  28. Fujimoto JG, Hee MR, Huang DH, et al. Optical coherence tomography: its history, how it works, and what its images show. In:  Schuman JS,  Puliafito CA,  Fujimoto JG editor. Everyday OCT. A Handbook for Clinicians and Technicians. chapter 3. Thorofare, NJ: Slack Incorporated; 2006;p. 87–120
  29. Gauderman WJ, Barlow WE. Sample size calculations for ophthalmologic studies. Arch Ophthalmol. 1992;110(5):690–692
  30. Giuffrè G. Optic disc drusen in tilted disc. Eur J Ophthalmol. 2005;15(5):647–651
  31. Giuffrè G. Tilted discs and central retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol. 1993;231(1):41–42
  32. Giuffrè G. Chorioretinal degenerative changes in the tilted disc syndrome. Int Ophthalmol. 1991;15(1):1–7
  33. Giuffrè G. Morning glory syndrome: clinical and electrofunctional study of three cases. Br J Ophthalmol. 1986;70(3):229–236
  34. Giuffrè G. Hypothesis on the pathogenesis of the papillary dysversion syndrome. J Fr Ophtalmol. 1985;8(8–9):565–572
  35. Giuffrè G, Anastasi M. Electrofunctional features of the tilted disc syndrome. Doc Ophthalmol. 1986;62(3):223–230
  36. Gordon MO, Beiser JA, Brandt JD, et al. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120(6):714–720
  37. Gündüz A, Evereklioglu C, Er H, Hepšen IF. Lenticular astigmatism in tilted disc syndrome. J Cataract Refract Surg. 2002;28(10):1836–1840
  38. Gürlü VP, Alýmgýl ML. Retinal nerve fiber analysis and tomography of the optic disc in eyes with tilted disc syndrome. Ophthalmic Surg Lasers Imaging. 2005;36(6):494–502
  39. Gürlü VP, Alimgil ML, Benian O. Topographical analysis of the visual field in tilted disk syndrome. Retina. 2002;22(3):366–368
  40. Hamada T, Tsukada T, Hirose T. Clinical and electrophysiological features of tilted disc syndrome. [Abstract] Jpn J Ophthalmol. 1987;31(2):265–273
  41. Herndon LW, Weizer JS, Stinnett SS. Central corneal thickness as a risk factor for advanced glaucoma damage. Arch Ophthalmol. 2004;122(1):17–21
  42. Hershenfeld SA, Sharpe JA. Monocular temporal hemianopia. Br J Ophthalmol. 1993;77(7):424–427
  43. Hittner HM, Borda RP, Justice J. X-linked recessive congenital stationary night blindness, myopia, and tilted discs. J Pediatr Ophthalmol Strabismus. 1981;18(1):15–20
  44. Hoh S, Greenfield D, Liebmann J, et al. Factors affecting image acquisition during scanning laser polarimetry. Ophthalmic Surg Lasers. 1998;29(7):545–551
  45. Hood D, Kardon R. A framework for comparing structural and functional measures of glaucomatous damage. Prog Retin Eye Res. 2007;26(6):688–710
  46. How AC, Tan GS, Chan YH, et al. Population prevalence of tilted and torted optic discs among an adult Chinese population in Singapore: the Tanjong Pagar Study. Arch Ophthalmol. 2009;127(7):894–899
  47. Jonas JB. Clinical implications of peripapillary atrophy in glaucoma. Curr Opin Ophthalmol. 2005;16(2):84–88
  48. Jonas JB. Biomorphometry and histomorphometry of the optic disc with special reference to the parapapillary region. Bull Soc Belge Ophthalmol. 1992;244:45–60
  49. Jonas JB, Gusek GC, Naumann GO. Optic disc, cup and neuroretinal rim size, configuration and correlations in normal eyes. Invest Ophthalmol Vis Sci. 1988;29(7):1151–1158
  50. Jonas JB, Gusek GC, Naumann GO. Optic disc morphometry in high myopia. Graefes Arch Clin Exper Ophthalmol. 1988;226:587–590
  51. Jonas JB, Kling F, Gründler AE. Optic disc shape, corneal astigmatism, and amblyopia. Ophthalmology. 1997;104(11):1934–1937
  52. Jonas JB, Nguyen XN, Gusek GC, et al. Parapapillary chorioretinal atrophy in normal and glaucoma eyes. I. Morphometric data. Invest Ophthalmol Vis Sci. 1989;30(5):908–918
  53. Kanski J. Tilted disc. In: Clinical Ophthalmology. A Systematic Approach. ed 6. London, Butterworth Heineman: Elsevier; 2008;p. 82
  54. Katz B, Hoyt WF. Intrapapillary and peripapillary hemorrhage in young patients with incomplete posterior vitreous detachment. Signs of vitreopapillary traction. Ophthalmology. 1995;102(2):349–354
  55. Kee C, Koo H, Ji Y, et al. Effect of optic disc size or age on evaluation of optic disc variables. Br J Ophthalmol. 1997;81(12):1046–1049
  56. Khairallah M, Chatti T, Messaoud R, et al. Peripapillary subretinal neovascularization associated with tilted disk syndrome. Retina. 1996;16(5):449–451
  57. Kline L, Arnold A, Eggenberger E, et al. Congenital tilted optic disc syndrome, in American Academy of Ophthalmology, Basic and Clinical Science Course, Section 5, Neuro-Ophthalmology. San Francisco, AAO, ed 2008–2009, pp 139–40
  58. Kokame G, Yamamoto I, Kishi S, et al. Intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage. Ophthalmology. 2004;111(5):926–930
  59. Kuprjanowicz L, Zarzycki A, Karczewicz D, et al. Objective retinal nerve fiber laser assessment by scanning laser polarimetry in patients with chiasmal compression. Klin Oczna. 2005;107(7–9):452–456
  60. Law S, Tamboli D, Giaconi J, et al. Characterization of retinal nerve fiber layer in nonglaucomatous eyes with tilted discs. Arch Ophthalmol. 2010;128(1):141–142
  61. Lempert P, Porter L. Dysversion of the optic disc and axial length measurements in a presumed amblyopic population. J AAPOS. 1998;2(4):207–213
  62. Leys AM, Cohen SY. Subretinal leakage in myopic eyes with a posterior staphyloma or tilted disk syndrome. Retina. 2002;22(5):659–665
  63. Lim L, Gazzard G, Chan YH, et al. Corneal biomechanics, thickness and optic disc morphology in children with optic disc tilt. Br J Ophthalmol. 2008;92(11):1461–1466
  64. Lin S, Singh K, Jampel H, et al. Optic nerve head and retinal nerve fiber analysis: a report by the American Academy of Ophthalmology. Ophthalmology. 2007;114(10):1937–1949
  65. Liu GT. Optic gliomas of the anterior visual pathway. Curr Opin Ophthalmol. 2006;17(5):427–431
  66. Malinowski SM, Pulido JS, Flickinger RR. The protective effect of the tilted disc syndrome in diabetic retinopathy. Arch Ophthalmol. 1996;114(2):230–231
  67. Manfre L, Vero S, Focarelli-Barone C, et al. Bitemporal pseudohemianopia related to the "tilted disk" syndrome: CT, MR, and fundoscopic findings. Am J Neuroradiol. 1999;20(9):1750–1751
  68. Mann I. Some suggestions on the embryology of congenital crescents. Br J Ophthalmol. 1923;7(8):359–373
  69. Manor RS. Temporal field defects due to nasal tilting of discs. Ophthalmologica. 1974;168(4):269–281
  70. Mashima Y, Kimura I, Yamamoto Y, et al. Optic disc excavation in the atrophic stage of Leber's hereditary optic neuropathy: comparison with normal tension glaucoma. Graefes Arch Clin Exp Ophthalmol. 2003;241(2):75–80
  71. Mauget-Faysse M, Cornut PL, Quaranta El-Maftouhi M, et al. Polypoidal choroidal vasculopathy in tilted disk syndrome and high myopia with staphyloma. Am J Ophthalmol. 2006;142(6):970–975
  72. Medeiros FA, Zangwill LM, Bowd C, et al. Use of progressive glaucomatous optic disk change as the reference standard for evaluation of diagnostic tests in glaucoma. Am J Ophthalmol. 2005;139(6):1010–1018
  73. Medeiros F, Zangwill L, Bowd C, et al. Comparison of the GDx VCC scanning laser polarimeter, HRT II confocal scanning laser ophthalmoscope, and stratus OCT optical coherence tomography for the detection of glaucoma. Arch Ophthalmol. 2004;122(6):827–837
  74. Milani P, Pece A, Moretti G, et al. Intravitreal bevacizumab for CNV-complicated tilted disk syndrome. Graefes Arch Clin Exp Ophthalmol. 2009;247(9):1179–1182
  75. Mitchell P, Hourihan F, Sandback J, et al. The relationship between glaucoma and myopia: The Blue Mountain Eye Study. Ophthalmology. 1999;106:2010–2015
  76. Miura G, Yamamoto S, Tojo N, et al. Foveal retinal detachment and retinoschisis without macular hole associated with tilted disc syndrome. Jpn J Ophthalmol. 2006;50(6):566–567
  77. Miyahara T, Kurimoto Y, Kurokawa T, et al. Alterations in retinal nerve fiber layer thickness following indirect traumatic optic neuropathy detected by nerve fiber analyzer, GDx-N. Am J Ophthalmol. 2003;136(2):361–364
  78. Monteiro ML, Medeiros FA, Ostroscki MR. Quantitative analysis of axonal loss in band atrophy of the optic nerve using scanning laser polarimetry. Br J Ophthalmol. 2003;87(1):32–37
  79. Monteiro ML, Moura FC, Medeiros FA. Scanning laser polarimetry with enhanced corneal compensation for detection of axonal loss in band atrophy of the optic nerve. Am J Ophthalmol. 2008;145(4):747–754
  80. Moschos MM, Margetis I, Papadimitriou S, et al. Clinical and multifocal–electroretinographic findings of congenital tilted disc syndrome associated with choroidal neovascularization: a case report. Doc Ophthalmol. 2007;115(2):121–124
  81. Moschos MM, Triglianos A, Rotsos T, et al. Tilted disc syndrome: an OCT and mfERG study. Doc Ophthalmol. 2009;119(1):23–28
  82. Nagai-Kusuhara A, Nakamura M, Kanamori A, et al. Evaluation of optic nerve head configuration in various types of optic neuropathy with Heidelberg Retina Tomograph. Eye. 2008;22(9):1154–1160
  83. Nagai-Kusuhara A, Nakamura M, Tatsumi Y, et al. Disagreement between Heidelberg Retina Tomograph and optical coherence tomography in assessing optic nerve head configuration of eyes with band atrophy and normal eyes. Br J Ophthalmol. 2008;92(10):1382–1386
  84. Nakanishi H, Tsujikawa A, Gotoh N, et al. Macular complications on the border of an inferior staphyloma associated with tilted disc syndrome. Retina. 2008;28(10):1493–1501
  85. Nakazawa M, Kurotaki J, Ruike H. Longterm findings in peripapillary crescent formation in eyes with mild or moderate myopia. Acta Ophthalmol. 2008;86(6):626–629
  86. Ornek K, Ozdemir M. Central corneal thickness in tilted disc syndrome. Optom Vis Sci. 2008;85(5):E350–E352
  87. Park KH, Caprioli J. Development of a novel reference plane for the Heidelberg retina tomograph with optical coherence tomography measurements. J Glaucoma. 2002;11(5):385–391
  88. Park CY, Kim YT, Kee C. Evaluation of the influence of tilt of optic disc on the measurement of optic disc variables obtained by optical coherence tomography and confocal scanning laser ophthalmoscopy. J Glaucoma. 2005;14(3):210–214
  89. Ponte F, Anastasi M, Lauricella M. Visual evoked potential latency and visual field evolution after normalization of intraocular pressure in glaucoma. Docum Ophthal Proc Ser. 1984;40:257–264
  90. Pro MJ, Pons ME, Liebmann JM, et al. Imaging of the optic disc and retinal nerve fiber layer in acute optic neuritis. J Neurol Sci. 2006;250(1–2):114–119
  91. Prost M, De Laey JJ. Choroidal neovascularization in tilted disc syndrome. Int Ophthalmol. 1988;12(2):131–135
  92. Quigley HA, Brown AE, Morrison JD, et al. The size and shape of the optic disc in normal human eyes. Arch Ophthalmol. 1990;108(1):51–57
  93. Ramrattan RS, Wolfs RC, Jonas JB, et al. Determinants of optic disc characteristics in a general population: The Rotterdam Study. Ophthalmology. 1999;106(8):1588–1596
  94. Riise D. The nasal fundus ectasia. Acta Ophthalmol (Suppl). 1975;126:3–108
  95. Rucker C. Bitemporal defects of the visual fields resulting from developmental anomalies of the optic disks. Arch Ophthalmol. 1946;35:546–554
  96. Saeed P, Rootman J, Nugent RA, et al. Optic nerve sheath meningiomas. Ophthalmology. 2003;110(10):2019–2030
  97. Saito H, Tomidokoro A, Sugimoto E, et al. Optic disc topography and peripapillary retinal nerve fiber layer thickness in nonarteritic ischemic optic neuropathy and open-angle glaucoma. Ophthalmology. 2006;113(8):1340–1344
  98. Saito H, Tomidokoro A, Tomita G, et al. Optic disc and peripapillary morphology in unilateral nonarteritic anterior ischemic optic neuropathy and age- and refraction-matched normals. Ophthalmology. 2008;115(9):1585–1590
  99. Salgarello T, Falsini B, Tedesco S, et al. Correlation of optic nerve head tomography with visual field sensitivity in papilledema. Invest Ophthalmol Vis Sci. 2001;42(7):1487–1494
  100. Seider MI, Lee RY, Wang D, et al. Optic disk size variability between African, Asian, white, Hispanic, and Filipino Americans using Heidelberg retinal tomography. J Glaucoma. 2009;18(8):595–600
  101. Sharma P, Sample P, Zangwill L, et al. Diagnostic tools for glaucoma detection and management. Surv Ophthalmol. 2008;53(Suppl 1):S17–S32
  102. Shiraki K, Mimura O, Shimo-Oku M. The tilted disc syndrome. Nippon Ganka Gakkai Zasshi. 1980;84(7):529–536
  103. Sibony P, Fourman S, Honkanen R, et al. Asymptomatic peripapillary subretinal hemorrhage: a study of 10 cases. J Neuroophthalmol. 2008;28(2):114–119
  104. Simon J, Aaby A, Drack A, et al. Optic nerve hypoplasia, in American Academy of Ophthalmology, Basic and Clinical Science Course, Section 6, Pediatric Ophthalmology and Strabismus. San Francisco, AAO, ed 2008–2009, pp 362–3
  105. Singh J. Echographic features of tilted optic disk. Ann Ophthalmol. 1985;17(6):382–384
  106. Sowka JW, Luong VV. Bitemporal visual field defects mimicking chiasmal compression in eyes with tilted disc syndrome. Optometry. 2009;80(5):232–242
  107. Sperduto RD, Seigel D, Roberts J, et al. Prevalence of myopia in the United States. Arch Ophthalmol. 1983;101(3):405–407
  108. Spry PD, Johnson CA. Identification of progressive glaucomatous visual field loss. Surv Ophthalmol. 2002;47:158–173
  109. Strouthidis N, Yang H, Downs JC, et al. Comparison of clinical and three-dimensional histomorphometric optic disc margin anatomy. Invest Ophthalmol Vis Sci. 2009;50(5):2165–2174
  110. Strouthidis N, Yang H, Reynaud JF. Comparison of clinical and spectral domain optical coherence tomography optic disc margin anatomy. Invest Ophthalmol Vis Sci. 2009;50(10):4709–4718
  111. Stur M. Congenital tilted disk syndrome associated with parafoveal subretinal neovascularization. Am J Ophthalmol. 1988;105(1):98–99
  112. Subei AM, Eggenberger ER. Optical coherence tomography: another useful tool in a neuro-ophthalmologist's armamentarium. Curr Opin Ophthalmol. 2009;20(6):462–466
  113. Susana R, Vessani RM. New findings in the evaluation of the optic disc in glaucoma diagnosis. Curr Opin Ophthalmol. 2007;18:122–128
  114. Swindale N, Stjepanovic G, Chin A, et al. Automated analysis of normal and glaucomatous optic nerve head topography images. Invest Ophthalmol Vis Sci. 2000;41(7):1740–1742
  115. Szily von A. Uber den Conus in heterotypischer Richtung. Graefes Arch Klin Experiment Ophthalmol. 1922;110:183–291
  116. Tarver-Carr ME, Miller NR. Tilted optic discs visualized by magnetic resonance imaging. J Neuroophthalmol. 2006;26(4):282–283
  117. Tate GW. The physiological basis for perimetry. In:  Drance SM,  Anderson D editor. Automatic Perimetry in Glaucoma: A Practical Guide. Orlando, FL: Grune & Stratton; 1985;p. 1–28
  118. Tatlıpınar S, Yagci B, Yaylalı V, et al. The effect of tilted disc syndrome on ocular hemodynamic measurements. Neuro-Ophthalmology. 2005;29:49–52
  119. Tay E, Seah SK, Chan SP, et al. Optic disk ovality as an index of tilt and its relationship to myopia and perimetry. Am J Ophthalmol. 2005;139(2):247–252
  120. Tezel G, Kolker AE, Kass MA, et al. Parapapillary chorioretinal atrophy in patients with ocular hypertension. I. An evaluation as a predictive factor for the development of glaucomatous damage. Arch Ophthalmol. 1997;115:1503–1508
  121. Tezel G, Kolker AE, Wax MB, et al. Parapapillary chorioretinal atrophy in patients with ocular hypertension. II. An evaluation of progressive changes. Arch Ophthalmol. 1997;115:1509–1514
  122. Theodossiadis PG, Grigoropoulos V, Emfietzoglou J, et al. Optical coherence tomography study of tilted optic disk associated with macular detachment. Graefes Arch Clin Exp Ophthalmol. 2006;244(1):122–124
  123. Tong L, Chan YH, Gazzard G, et al. Heidelberg retinal tomography of optic disc and nerve fiber layer in singapore children: variations with disc tilt and refractive error. Invest Ophthalmol Vis Sci. 2007;48(11):4939–4944
  124. Tosti G. Serous macular detachment and tilted disc syndrome. Ophthalmology. 1999;106(8):1453–1455
  125. Trick GL, Bhatt SS, Dahl D, et al. Optic disc topography in pseudopapilledema: a comparison to pseudotumor cerebri. J Neuroophthalmol. 2001;21(4):240–244
  126. Trick GL, Calotti FY, Skarf B. Advances in imaging of the optic disc and retinal nerve fiber layer. J Neuroophthalmol. 2006;26(4):284–295
  127. Trip SA, Schlottmann PG, Jones SJ, et al. Quantification of optic nerve head topography in optic neuritis: a pilot study. Br J Ophthalmol. 2006;90(9):1128–1131
  128. Turbin RE, Pokorny K. Diagnosis and treatment of orbital optic nerve sheath meningioma. Cancer Control. 2004;11(5):334–341
  129. Vongphanit J, Mitchell P, Wang JJ. Population prevalence of tilted optic disks and the relationship of this sign to refractive error. Am J Ophthalmol. 2002;133(5):679–685
  130. Vuori ML, Mäntyjärvi M. Tilted disc syndrome may mimic false visual field deterioration. Acta Ophthalmol. 2008;86(6):622–625
  131. Vuori ML, Mäntyjärvi M. Tilted disc syndrome and colour vision. Acta Ophthalmol Scand. 2007;85(6):648–652
  132. Wakakura M, Ishikawa S. Neuro-ophthalmic aspects of vascular disease. Curr Opin Ophthalmol. 1994;5(6):18–22
  133. Weale RA. Epidemiology of refractive errors and presbyopia. Surv Ophthalmol. 2003;48(5):515–543
  134. Weiss A. Ocular malformations. Ophthalmol Clin North Am. 1990;3:131–148
  135. Wijngaarde R, van Lith GH. Electrodiagnostics of the tilted disc syndrome. Doc Ophthalmol. 1981;50(2):365–369
  136. Wu SY, Nemesure B, Leske MC. Refractive errors in a black adult population: the Barbados eye study. Invest Ophthalmol Vis Sci. 1999;40:2179–2184
  137. You QS, Xu L, Jonas JB. Tilted optic discs: the Beijing eye study. Eye. 2008;22(5):728–729
  138. Young SE, Walsh FB, Knox DL. The tilted disk syndrome. Am J Ophthalmol. 1976;82(1):16–23
  139. Yu S, Tanabe T, Hangai M, et al. Scanning laser polarimetry with variable corneal compensation and optical coherence tomography in tilted disk. Am J Ophthalmol. 2006;142(3):475–482

 The authors reported no proprietary or commercial interest in any product mentioned or concept discussed in this article.

PII: S0039-6257(10)00039-1

doi: 10.1016/j.survophthal.2010.01.002

Survey of Ophthalmology
Volume 55, Issue 5 , Pages 403-428 , September 2010