Survey of Ophthalmology
Volume 44 , Pages S163-S168 , January 2000

Adjunctive Therapy With Brinzolamide 1% Ophthalmic Suspension (Azopt®) in Patients With Open-Angle Glaucoma or Ocular Hypertension Maintained on Timolol Therapy

References 

  1. Camras C, Brinzolamide Primary Therapy Study Group . A triple-masked, primary therapy study of the efficacy and safety of bid and tid-dosed brinzolamide 1% compared to tid-dosed dorzolamide 2% and bid-dosed timolol 0.5% (abstract). Invest Ophthalmol Vis Sci. 1997;38(suppl 4):S560
  2. Hurvitz LM, Kaufman PL, Robin AL, et al.  New developments in the drug treatment of glaucoma. Drugs. 1991;41:514–532
  3. March W, Silver L, Brinzolamide Long-Term Therapy Study Group . The long-term safety and efficacy of brinzolamide (Azopt™), a new topical carbonic anhydrase inhibitor, in patients with open angle glaucoma and ocular hypertension (abstract). Invest Ophthalmol Vis Sci. 1998;39(suppl 4):S199
  4. Sall K, Brinzolamide Primary Therapy Study Group . The efficacy and safety of brinzolamide 1% ophthalmic suspension (Azopt®) as a primary therapy in patients with primary open-angle glaucoma or ocular hypertension. Surv Ophthalmol. 2000;44(suppl 2):S155–S162
  5. Shin D, Brinzolamide Adjunctive Therapy Study Group . A triple-masked, placebo-controlled, adjunctive therapy study of the efficacy and safety of tid-dosed brinzolamide compared to tid-dosed placebo when used adjunctively to timolol 0.5% (abstract). Invest Ophthalmol Vis Sci. 1997;38(suppl 4):S559
  6. Silver L, Brinzolamide Primary Therapy Study Group . Clinical efficacy and safety of brinzolamide (Azopt™), a new topical carbonic anhydrase inhibitor for primary open-angle glaucoma and ocular hypertension. Am J Ophthalmol. 1998;126:400–408
  7. Stewart R, Brinzolamide Comfort Study Group . The ocular comfort of tid-dosed brinzolamide 1.0% compared to tid-dosed dorzolamide 2.0% in patients with primary open-angle glaucoma or ocular hypertension (abstract). Invest Ophthalmol Vis Sci. 1997;38(suppl 4):S559
  8. Strahlman ER, Vogel R, Tiping R, Clineschmidt CM. The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure (the Dorzolamide Additivity Study Group). Ophthalmology. 1996;103:1283–1293

☆ Dr. Shin has no commercial or proprietary interest in the products or concepts discussed in this article.

☆☆ This study was funded by Alcon Research, Ltd., Fort Worth, TX, USA.

PII: S0039-6257(99)00106-X

Survey of Ophthalmology
Volume 44 , Pages S163-S168 , January 2000

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