Survey of Ophthalmology RSS feed: Articles in Press. Survey of Ophthalmology is a clinically oriented review journal designed to keep ophthalmologists up to date. Comprehensive major review articles, written by experts and stringently refereed, integrate the literature on subjects selected for their clinical importance. Survey also includes feature articles, section reviews, book reviews, and abstracts. To view video files associated with published manuscripts, click here .http://www.surveyophthalmol.com//inpress?rss=yesElsevier Inc.en © 2010 Elsevier Inc. All rights reserved. Survey of Ophthalmology0039-62572010-08-16 © 2010 Elsevier Inc. All rights reserved. healthpermissions@elsevier.comhttp://www.surveyophthalmol.com/article/PIIS0039625710001116/abstract?rss=yesAbstract: A 58-year-old white man presented with a second episode of vision loss in the same eye. Diagnostic evaluations conducted at each episode were unrevealing for an underlying etiology, and a presumptive diagnosis of recurrent non-arteritic anterior ischemic optic neuropathy (NAION) was made. The evaluation of recurrent NAION is discussed.Not Again! - Corrected ProofKathryn L. Pepple, M. Tariq Bhatti, Rod Foroozan10.1016/j.survophthal.2010.05.002Survey of Ophthalmology (2010)2010-08-16Survey of Ophthalmology2010-08-16CLINICAL CHALLENGEShttp://www.surveyophthalmol.com/article/PIIS0039625710000871/abstract?rss=yesAbstract: Weber-Christian disease is a febrile, relapsing, non-suppurative panniculitis of unknown etiology. Lobular panniculitis is the essential feature in biopsy specimens and evolves through three recognizable stages. We report a case of Weber-Christian disease with bilateral orbital involvement, at different stages, affecting the orbital fat along with enophthalmos in one orbit, and the upper preaponeurotic fat pad in the other. Weber-Christian disease was refractory to treatment with conventional immunosuppressive regimens; however, early inflammatory—but not chronic fibrotic—orbital lesions responded dramatically to anti-tumor necrosis factor (TNF) therapy. A literature review revealed five additional cases of orbital Weber-Christian disease, none treated with anti-TNF antibodies. Of these, four presented initially with proptosis, representing early stages of inflammation, and two subsequently developed enophthalmos, representing late, inactive stage of the disease. Although orbital Weber-Christian disease is rare, ophthalmologists need to be aware of this entity. Depending on the stage of inflammation, Weber-Christian disease should be included in the differential diagnosis of both proptosis and enophthalmos. Anti-TNF antibodies can successfully treat patients at the early inflammatory stage.Orbital Lobular Panniculitis in Weber-Christian Disease: Sustained Response to Anti-TNF Treatment and Review of the Literature - Corrected ProofIoannis Mavrikakis, Thomas Georgiadis, Kalliopi Fragiadaki, Petros P. Sfikakis10.1016/j.survophthal.2010.05.001Survey of Ophthalmology (2010)2010-08-11Survey of Ophthalmology2010-08-11CLINICAL PATHOLOGIC REVIEWShttp://www.surveyophthalmol.com/article/PIIS0039625709003154/abstract?rss=yesAbstract: A 70-year-old man presented complaining of lid and facial drooping and facial numbness, which progressed over several months. Magnetic resonance imaging of the head showed an enlarged right cavernous sinus. His past medical history was remarkable to squamous cell carcinoma of the face. The patient underwent a craniotomy with biopsy of the cavernous sinus that confirmed malignancy. High index of suspicion in a patient that presents facial drooping and/or numbness should alert ophthalmologists about the occurrence of perineural spread of a previous malignant lesion of the skin.The Bell's Toll - Corrected ProofLuciano Mesquita Simão, Ann P. Murchison, Jurij R. Bilyk, Peter A.D. Rubin10.1016/j.survophthal.2009.12.004Survey of Ophthalmology (2010)2010-05-10Survey of Ophthalmology2010-05-10CLINICAL CHALLENGES